Anti-Human/Mouse PAPPA Polyclonal Antibody

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10632
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PAPPA
Specificity High levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q13219
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names ASBABP2,Aspecific BCL2 ARE binding protein 2,Differentially placenta 1 expressed protein,DIPLA1,EC 3.4.24.79,IGF dependent IGFBP 4 protease,IGF-dependent IGFBP-4 protease,IGFBP 4ase,IGFBP-4ase,IGFBP4ase,Insulin like growth factor dependent IGF binding protein 4 protease,Insulin-like growth factor-dependent IGF-binding protein 4 protease,PAPA,PAPP A,PAPP-A,PAPP1,PAPPA,PAPPA1,Pappalysin 1 precursor,Pappalysin-1,Pregnancy Associated Plasma Protein A,Pregnancy associated plasma protein A pappalysin 1,Pregnancy-associated plasma protein A
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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