Anti-Human/Mouse OS9 Polyclonal Antibody

This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11840
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human OS9
Specificity Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma OSA-CL and rhabdomyosarcoma RH30 cell lines. Isoform 2 is the major isoform detected in all cell types examined.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q13438
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Amplified in osteosarcoma 9,amplified in osteosarcoma,ERLEC2,OS-9,Os9,OS9,Osteosarcoma amplified 9 endoplasmic reticulum lectin,Protein OS-9
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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