Anti-Human/Mouse NLRP12 Polyclonal Antibody

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10484
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NLRP12
Specificity Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P59046
Concentration 0.6 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names CLR19.3,FCAS2,Monarch 1,Monarch-1,NACHT,leucine rich repeat and PYD containing 12,NACHT,LRR and PYD containing protein 12,NACHT,LRR and PYD domains-containing protein 12,NAL12,NLR family,pyrin domain containing 12,NLRP12,Nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 12,OTTHUMP00000067227,PAN6,PYPAF7,PYRIN containing APAF1 like protein 7,PYRIN-containing APAF1-like protein 7,Regulated by nitric oxide,RNO,RNO2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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