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Anti-Human/Mouse NEIL3 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.NEIL3 (Nei Like DNA Glycosylase 3) is a Protein Coding gene. Among its related pathways are Telomere C-strand (Lagging Strand) Synthesis. GO annotations related to this gene include nucleic acid binding and single-stranded DNA binding. An important paralog of this gene is NEIL2.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05247
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human NEIL3
Specificity Detected in thymus and testis. Expressed at higher levels in tumor tissue than in the corresponding normal tissues except for pancreas and testis where expression is higher in normal than tumor tissue.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8TAT5
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IHC-p,ELISA
Other Names 123,AI449477,BC034753,C85903,DNA glycosylase FPG2,DNA glycosylase hFPG2,DNA glycosylase/AP lyase Neil3,EC 3.2.2.-,EC 4.2.99.18,Endonuclease 8-like 3,Endonuclease VIII-like 3,FGP2,FLJ10858,FPG2,hFPG2,hNEI3,MGC27861,MGC36916,Nei endonuclease VIII-like 3 (E. coli),nei endonuclease VIII-like 3,Nei like 3 (E. coli),Nei-like protein 3,NEIL3,NEIL3,OTTHUMP00000218810,RGD1310562
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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