Anti-Human/Mouse MYSM1 Polyclonal Antibody

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10408
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human MYSM1
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q5VVJ2
Concentration 0.7 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names 2A-DUB,2ADUB,Histone H2A deubiquitinase,Histone H2A deubiquitinase MYSM1,KIAA1915,Myb like SWIRM and MPN domains 1,Myb like,SWIRM and MPN domain containing protein,Myb like,SWIRM and MPN domains 1,Myb-like,Myb-like,SWIRM and MPN domains 1,MYSM 1,mysm1,MYSM1 Myb-like,SWIRM and MPN domains 1,MYSM1,RP4-592A1.1,SWIRM and MPN domain-containing protein 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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