Anti-Human/Mouse MSC Polyclonal Antibody

The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.MSC (Musculin) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription corepressor activity. An important paralog of this gene is TCF21.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05175
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Musculin
Specificity Expressed in lymphoid tissues, B-cell lines and activated B-cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O60682
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names ABF-1,ABF1,Activated B cell factor 1,Activated B-cell factor 1,bHLHa22,Class A basic helix-loop-helix protein 22,Msc,MUSC,Musculin,MYOR
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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