Anti-Human/Mouse/Monkey SOX-8/9/17/18 Polyclonal Antibody

SOX8 (SRY-Box 8) is a Protein Coding gene. Diseases associated with SOX8 include Myoblastoma and Alpha Thalassemia-Intellectual Disability Syndrome Type 1. Among its related pathways are ERK Signaling and Preimplantation Embryo. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is SOX9. SOX9 (SRY-Box 9) is a Protein Coding gene. Diseases associated with SOX9 include Campomelic Dysplasia and Pierre Robin Syndrome. Among its related pathways are Signaling by Wnt and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. An important paralog of this gene is SOX10. SOX17 (SRY-Box 17) is a Protein Coding gene. Diseases associated with SOX17 include Vesicoureteral Reflux 3 and Familial Vesicoureteral Reflux. Among its related pathways are Mesodermal Commitment Pathway and Signaling by Wnt. An important paralog of this gene is SOX7. SOX18 (SRY-Box 18) is a Protein Coding gene. Diseases associated with SOX18 include Hypotrichosis-Lymphedema-Telangiectasia Syndrome and Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome. Among its related pathways are ERK Signaling. An important paralog of this gene is SOX17.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05891
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Sox-8/9/17/18
Specificity Expressed in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach and small intestine than in colon and rectum.1 Publication
Isotype IgG
Reacitivity Human,Mouse,Monkey
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names SOX8,Transcription factor SOX-8,SOX9,Transcription factor SOX-9,SOX17,Transcription factor SOX-17,SOX18,Transcription factor SOX-18
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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