Anti-Human/Mouse/Monkey GPR132 Polyclonal Antibody

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants.GPR132 (G Protein-Coupled Receptor 132) is a Protein Coding gene. Diseases associated with GPR132 include Inclusion Conjunctivitis. Among its related pathways are RET signaling and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is GPR4.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04105
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human G2A
Specificity Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.
Isotype IgG
Reacitivity Human,Mouse,Monkey
Clone
Uniprot Q9UNW8
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IF,ELISA
Other Names G Protein Coupled Receptor G2A,G2 accumulation protein,G2A,GP132,GPR132,Probable G-protein coupled receptor 132
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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