Anti-Human/Mouse/Monkey G3BP1 Polyclonal Antibody

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04106
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human G3BP1 around the non-phosphorylation site of Ser232.
Specificity Ubiquitous.
Isotype IgG
Reacitivity Human,Mouse,Monkey
Clone
Uniprot Q13283
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names ATP dependent DNA helicase VIII,ATP-dependent DNA helicase VIII,G3BP,G3BP stress granule assembly factor 1,G3BP-1,G3bp1,G3BP1,GAP binding protein,GAP SH3 domain binding protein 1,GAP SH3 domain-binding protein 1,GTPase activating protein (SH3 domain) binding protein 1,hDH VIII,Human DNA helicase VIII,MGC111040,Ras GTPase activating protein binding protein 1,Ras GTPase activating protein SH3 domain binding protein,Ras GTPase-activating protein-binding protein 1,RasGAP associated endoribonuclease G3BP
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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