Anti-Human/Mouse/Monkey Frizzled 10 Polyclonal Antibody

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04089
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Frizzled-10
Specificity Highest levels in the placenta and fetal kidney, followed by fetal lung and brain. In adult brain, abundantly expressed in the cerebellum, followed by cerebral cortex, medulla and spinal cord; very low levels in total brain, frontal lobe, temporal lobe and putamen. Weak expression detected in adult brain, heart, lung, skeletal muscle, pancreas, spleen and prostate.
Isotype IgG
Reacitivity Human,Mouse,Monkey
Clone
Uniprot Q9ULW2
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names CD 350,CD 350 antigen,CD350,Frizzled (Drosophila) homolog 10,Frizzled-10,FZ 10,Fz-10,FZ10,FZD 10,FZD10,FZD10,FzE 7,FzE7,hFz 10,hFz10
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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