Anti-Human/Mouse/Monkey ETAR Polyclonal Antibody

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03845
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human ETAR
Specificity Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.
Isotype IgG
Reacitivity Human,Mouse,Monkey
Clone
Uniprot P25101
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names Ednra,EDNRA,Endothelin 1 receptor precursor,Endothelin 1 specific receptor,Endothelin A receptor,Endothelin ET A receptor,Endothelin receptor ET1 specific type,Endothelin receptor subtype A,Endothelin receptor type A,Endothelin-1 receptor,ET A,ET-A,ETA,ETA R,ETA-R,ETAR,ETRA,G protein coupled receptor,hET AR,hET-AR,MFDA
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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