Anti-Human/Mouse MINK1 Polyclonal Antibody

This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. MINK1 (Misshapen Like Kinase 1) is a Protein Coding gene. Among its related pathways are Cellular Senescence and Angiopoietin Like Protein 8 Regulatory Pathway. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TNIK.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04982
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human MINK1
Specificity Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal muscle, pancreas and testis.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8N4C8
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names B55,GCK family kinase MiNK,hMINK,Map4k6,MAPK/ERK kinase kinase kinase 6,MEK (MAP/ERK) kinase kinase 6,MEK kinase kinase 6,MEKKK6,MGC21111,MINK 1,MINK,MINK1,Misshapen like kinase 1,Misshapen NIKs Related kinase,Misshapen/NIK related kinase,Mitogen activated protein kinase kinase kinase kinase 6,RP23-122P1.6,Ysk2,ZC3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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