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Anti-Human/Mouse MAP4K2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12738
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human MAP4K2
Specificity Highly expressed in germinal center but not mantle zone B-cells. Also expressed in lung, brain and placenta and at lower levels in other tissues examined.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q12851
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names B lymphocyte serine/threonine protein kinase,B lymphocyte serine/threonine-protein kinase,BL44,GC kinase,GCK,Germinal center kinase,germinal centre kinase (GC kinase),M4K2,Map4k2,MAPK/ERK kinase kinase kinase 2,MEK kinase kinase 2,MEKKK 2,Mitogen activated protein kinase kinase kinase kinase 2,Mitogen-activated protein kinase kinase kinase kinase 2,Rab8 interacting protein,Rab8 interacting protein,formerly,Rab8-interacting protein,RAB8IP,RAB8IP,formerly
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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