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Anti-Human/Mouse KRT2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06704
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human KRT2
Specificity Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P35908
Concentration 0.2 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names CK 2e,Cytokeratin-2e,Epithelial keratin-2e,K2e,Keratin type II cytoskeletal 2 epidermal,Keratin-2 epidermis,KRT2,KRT2A,KRT2E,Type-II keratin Kb2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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