Anti-Human/Mouse KIAA1524 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Protein CIP2A also known as cancerous inhibitor of PP2A (CIP2A) is a protein that in humans is encoded by the KIAA1524 gene. Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells. Inhibition of PP2A activity is a prerequisite for human cell transformation. However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA12353
Size	100μl
Host Type	Rabbit
Immunogen	Recombinant protein of human KIAA1524
Specificity	Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level).
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q8TCG1
Concentration	0.5 mg/mL
Dilution	WB 1:500-1:2000
Formulation
Application	WB,ELISA
Other Names	Cancerous inhibitor of PP2A,Cancerous Inhibitor of Protein Phosphatase 2A,CIP2A,CIP2A,FLJ12850,Kiaa1524,MGC163436,p90,p90 autoantigen,Protein CIP2A
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse KIAA1524 Polyclonal Antibody

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