Anti-Human/Mouse KAT2B Polyclonal Antibody

Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02478
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human PCAF around the non-acetylation site of K428.
Specificity Ubiquitously expressed but most abundant in heart and skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q92831
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names CAF,CREBBP associated factor,GCN5,GCN5L,GCN5L1,Histone acetylase PCAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF,K(lysine) acetyltransferase 2B,KAT2B,KAT2B,Lysine acetyltransferase 2B,P,P/CAF,p300/CBP associated factor,P300/CBP-associated factor,Pcaf
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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