Anti-Human/Mouse ITLN1 Polyclonal Antibody

Intelectin-1 also known as the intestinal lactoferrin receptor is a protein that in humans is encoded by the ITLN1 gene.Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin. Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11974
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ITLN1
Specificity Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8WWA0
Concentration 0.2 mg/mL
Dilution WB 1:1000-1:5000
Formulation
Application WB,ELISA
Other Names Endothelial lectin HL 1,Endothelial lectin HL-1,FLJ20022,Galactofuranose binding lectin,Galactofuranose-binding lectin,hIntL,HL 1,HL1,Intelectin,Intelectin 1,Intelectin-1,Intestinal lactoferrin receptor,INTL,ITLN,ITLN-1,ITLN1,ITLN1,LFR,Omentin,OTTHUMP00000027882
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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