Anti-Human/Mouse ITGA6 Polyclonal Antibody

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine witHuman, Mouseultiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08606
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human ITGA6
Specificity Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P23229
Concentration 0.4 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Alpha6p,CD49 antigen-like family member F,CD49f,Integrin alpha6B,Integrin,alpha 6,ITA6,ITGA6,ITGA6B,Processed integrin alpha-6,VLA 6,VLA-6
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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