Anti-Human/Mouse HDAC5/9 Polyclonal Antibody

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC5 (Histone Deacetylase 5) is a Protein Coding gene. Diseases associated with HDAC5 include Polycystic Kidney Disease, Adult Type I. Among its related pathways are PEDF Induced Signaling and Phospholipase-C Pathway. GO annotations related to this gene include transcription factor binding and transcription corepressor activity. An important paralog of this gene is HDAC4. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 (Histone Deacetylase 9) is a Protein Coding gene. Diseases associated with HDAC9 include Gastrointestinal Neuroendocrine Tumor and Cutaneous T Cell Lymphoma. Among its related pathways are PEDF Induced Signaling and Phospholipase-C Pathway. GO annotations related to this gene include transcription factor binding and histone deacetylase binding. An important paralog of this gene is HDAC5.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04371
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human HDAC5/9 around the non-phosphorylation site of Ser259/220.
Specificity Ubiquitous.Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names HDAC5,KIAA0600,Histone deacetylase 5,HD5,Antigen NY-CO-9,HDAC9,HDAC7,HDAC7B,HDRP,KIAA0744,MITR,Histone deacetylase 9,HD9,Histone deacetylase 7B,HD7,HD7b,Histone deacetylase-related protein,MEF2-interacting transcription rep
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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