Anti-Human/Mouse HAMP Polyclonal Antibody

Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01929
Size 100μl
Host Type Rabbit
Immunogen Recombinant Human Hepcidin protein
Specificity Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P81172
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names Hamp,HEPC,HEPC,Hepc20,Hepc25,HEPCIDIN,Hepcidin 20,Hepcidin 25,Hepcidin antimicrobial peptide,Hepcidin-20,Hepcidin25,HFE2,HFE2B,LEAP 1,LEAP-1,LEAP1,Liver expressed antimicrobial peptide,Liver-expressed antimicrobial peptide 1,PLTR,Putative liver tumor regressor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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