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Anti-Human/Mouse GPR124 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
TEM5 (G-protein coupled receptor 124) and TEM7 (plexin domain containing 1). TEMs are associated with the cell surface membrane at low levels in normal human and mouse tissues. TEM5 is a seven-pass transmembrane receptor, whereas TEM1, TEM7 and TEM8 span the membrane once. TEM5 expression is elevated during tumor angiogenesis and neoangiogenesis. TEM7 is highly expressed in tumor endothelium and neurons. Therefore, TEM5 and TEM7 may be suitable targets for the development of antiangiogenic therapies.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09128
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human GPR124
Specificity Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q96PE1
Concentration 0.5 mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300
Formulation
Application WB,IHC,ELISA
Other Names DKFZp434C211,DKFZp434J0911,FLJ14390,G protein coupled receptor 124,G-protein coupled receptor 124,GP124,GPR 124,Gpr124,KIAA1531,TEM 5,TEM5,Tumor endothelial marker 5,Tumor endothelial marker 5 precursor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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