Anti-Human/Mouse FUS Polyclonal Antibody

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07588
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human FUS
Specificity Ubiquitous.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P35637
Concentration 0.5 mg/mL
Dilution IHC 1:30-150, ELISA 1:2000-10000
Formulation
Application IHC,ELISA
Other Names 75 kDa DNA pairing protein,75 kDa DNA-pairing protein,ALS6,Amyotrophic lateral sclerosis 6,fus,FUS CHOP,Fus like protein,FUS,FUS1,Fused in sarcoma,Fusion (involved in t(12;16) in malignant liposarcoma),Fusion derived from t(12;16) malignant liposarcoma,Fusion gene in myxoid liposarcoma,Heterogeneous nuclear ribonucleoprotein P2,hnRNP P2,hnRNPP2,Oncogene FUS,Oncogene TLS,POMp75,RNA binding protein FUS,RNA-binding protein FUS,TLS,TLS CHOP,Translocated in liposarcoma,Translocated in liposarcoma protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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