Anti-Human/Mouse FOXD3 Polyclonal Antibody

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03972
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human FoxD3
Specificity Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9UJU5
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names AIS1,forkhead box D3,Forkhead box protein D3,foxd3,FOXD3,Genesis,HFH2,HNF3/FH transcription factor genesis,VAMAS2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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