Anti-Human/Mouse ESPL1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA09883
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human ESPL1
Specificity
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q14674
Concentration	0.5 mg/mL
Dilution	WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application	WB,IHC,ELISA
Other Names	Caspase like protein ESPL1,Caspase-like protein ESPL1,ESP 1,ESP1,ESPL 1,Espl1,ESPL1,Extra spindle poles like 1,Extra spindle poles like 1 protein,Extra spindle poles-like 1 protein,FLJ46492,KIAA0165,Separase,Separin,Similar to fission yeast cut1and gene,SSE
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse ESPL1 Polyclonal Antibody

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