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Anti-Human/Mouse EPPIN Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated witHuman, Mouseale infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09868
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human EPPIN
Specificity In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O95925
Concentration 0.7 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Cancer/testis antigen 71,CT 71,CT71,dJ461P17.2,Epididymal protease inhibitor,EPPIN 1,EPPIN 2,EPPIN 3,Eppin,EPPIN1,EPPIN2,EPPIN3,Protease inhibitor WAP7,Serine peptidase inhibitor like with Kunitz and WAP domains 1 (eppin),Serine peptidase inhibitor like with Kunitz and WAP domains 1,SPINLW 1,WAP 7,WAP four disulfide core domain 7,WAP four disulfide core domain protein 7,WAP7,WFDC 7,WFDC7
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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