Anti-Human/Mouse EPHA2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Induces apoptosis in a p53/TP53-independent, caspase-8-dependent manner.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA03761
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the N-terminal region of human EphA2
Specificity	Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g., skin, intestine, lung, and ovary.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	P29317
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, ELISA 1:40000
Formulation
Application	WB,ELISA
Other Names	ARCC2,AW545284,CTPA,CTPP1,CTRCT6,EC 2.7.10.1,Eck,Eph receptor A2,EPHA2,EPHA2,Ephrin receptor,Ephrin receptor EphA2,Ephrin type A receptor 2,Ephrin type-A receptor 2,Epithelial cell kinase,Epithelial cell receptor protein tyrosine kinase,Myk 2,Myk2,Sek 2,Sek2,Soluble EPHA2 variant 1,Tyrosine protein kinase receptor ECK,Tyrosine-protein kinase receptor ECK,Tyrosine-protein kinase receptor MPK-5,Tyrosine-protein kinase receptor SEK-2
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse EPHA2 Polyclonal Antibody

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