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Anti-Human/Mouse ELF5 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03722
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Elf-5
Specificity Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9UKW6
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IF,ELISA
Other Names E74 like factor 5 (ets domain transcription factor),E74 like factor 5,E74-like factor 5,ELF 5,ELF5,ELF5,Epithelium restricted ESE 1 related Ets factor,Epithelium restricted ESE1 related Ets factor,Epithelium specific Ets transcription factor 2,Epithelium-restricted ESE-1-related Ets factor,Epithelium-specific Ets transcription factor 2,ESE 2,ESE-2,ESE2,Ets domain TF,Ets domain transcription factor,ETS related transcription factor Elf 5,ETS related transcription factor Elf5,ETS-related transcription factor Elf-5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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