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Anti-Human/Mouse EID3 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
EID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09842
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human EID3
Specificity Highly expressed in testis.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8N140
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names E1A-like inhibitor of differentiation 3,EID 3,EID-1-like inhibitor of differentiation 3,EID-3,EID3,EID3,EP300 interacting inhibitor of differentiation 3,EP300-interacting inhibitor of differentiation 3,FLJ25832,Non-SMC element 4,S. cerevisiae,homolog of,B,Non-structural maintenance of chromosomes element 4 homolog B,NSE4B,NSMCE4B
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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