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Anti-Human/Mouse EEA1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking. The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns(3)P), targeting EEA1 to early endosomes. The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin. Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06201
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human EEA1.
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q15075
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names Early endosome antigen 1,Early endosome antigen 1,162kD,Early endosome associated protein,EEA 1,EEA1,EEA1,Endosome associated protein p162,Endosome-associated protein p162,MST105,MSTP105,ZFYVE2,Zinc finger FYVE domain containing protein 2,Zinc finger FYVE domain-containing protein 2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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