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Anti-Human/Mouse DTX1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Protein deltex-1 is a protein that in humans is encoded by the DTX1 gene. Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. DTX1 has been shown to interact with EP300. Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11359
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human DXT1
Specificity Widely expressed. Strongly expressed in blood vessel. Also expressed in embryonic nervous system, pancreas, lung, adrenal gland, digestive tube and muscles. Expressed in MZB cells and developing B- and T-cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q86Y01
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Deltex 1,E3 ubiquitin ligase,Deltex homolog 1 (Drosophila),Deltex homolog 1,Deltex protein 1,Deltex-1,Deltex1,dtx1,DTX1,E3 ubiquitin protein ligase DTX1,E3 ubiquitin-protein ligase DTX1,FXI-T1,Fxit 1,Fxit1,hDTX1,hDx 1,mDTX1,Protein deltex 1,Protein deltex-1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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