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Anti-Human/Mouse DSCR1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09894
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human RCAN1
Specificity Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P53805
Concentration 0.4 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names Adapt 78,Adapt78,Calcipressin 1,Calcipressin-1,Calcium and oxidant inducible mRNA,CSP 1,CSP1,Down syndrome candidate region 1,Down syndrome critical region gene 1,Down syndrome critical region protein 1,DSC 1,DSC1,DSCR 1,DSCR1,MCIP 1,MCIP1,Modulatory calcineurin interacting protein 1,Myocyte enriched calcineurin interacting protein 1,Myocyte-enriched calcineurin-interacting protein 1,Near DSCR proline rich protein,RCAN1,RCAN1,RCN 1,RCN1,Regulator of calcineurin 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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