Anti-Human/Mouse CYBB Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA10565
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human CYBB
Specificity	Detected in neutrophils (at protein level).
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	P04839
Concentration	0.7 mg/mL
Dilution	IHC 1:50-1:200
Formulation
Application	IHC,ELISA
Other Names	AMCBX2,CGD,CGD91-phox,CY24B,CYBB,Cytochrome b 245,beta polypeptide,Cytochrome b(558) beta chain,Cytochrome b(558) subunit beta,Cytochrome b-245 heavy chain,Cytochrome b558 subunit beta,GP91 PHOX,gp91-1,gp91-phox,GP91PHOX,Heme-binding membrane glycoprotein gp91phox,NADPH oxidase 2,Neutrophil cytochrome b 91 kDa polypeptide,NOX2,p22 phagocyte B-cytochrome,P91 PHOX,p91-PHOX,Superoxide-generating NADPH oxidase heavy chain subunit
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse CYBB Polyclonal Antibody

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