Anti-Human/Mouse CUEDC2 Polyclonal Antibody

CUEDC2 is involved in ubiquitin- and proteasome-mediated degradation of progesterone receptor and estrogen receptor (ER)-alpha.CUEDC2 reduced PRB protein content and promoted progesterone-induced PRB degradation via the ubiquitin-proteasome pathway.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12303
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CUEDC2
Specificity Significantly up-regulated in breast tumor tissues compared with matched adjacent normal tissues (at protein level). Levels inversely correlate with ESR1 in breast cancers and are lower in low-grade tumors compared to high-grade tumors.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9H467
Concentration 0.7 mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300
Formulation
Application WB,IHC,ELISA
Other Names bA18I14.5,C10orf66,Chromosome 10 open reading frame 66,CUE domain containing 2,CUE domain-containing protein 2,CUED2,CUED2,Cuedc2,MGC2491,OTTHUMP00000020368
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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