Anti-Human/Mouse CRADD Polyclonal Antibody

The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11788
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CRADD
Specificity Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P78560
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names CASP2 and RIPK1 domain containing adaptor with death domain,Caspase and RIP adapter with death domain,Caspase and RIP adaptor with death domain,Cradd,CRADD,Death adaptor molecule RAIDD,Death domain containing protein CRADD,Death domain-containing protein CRADD,MGC9163,RIP associated ICH1/CED3 homologous protein with death domain,RIP associated protein with a death domain,RIP-associated protein with a death domain
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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