Anti-Human/Mouse COPS5 Polyclonal Antibody

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04640
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human JAB1
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q92905
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names 38 kDa Mov34 homolog,COP9 (constitutive photomorphogenic) homolog subunit 5,COP9 constitutive photomorphogenic homolog subunit 5,COP9 signalosome complex subunit 5,COP9 signalosome subunit 5,Cop9 subunit 5,COPS 5,cops5,CSN 5,CSN5,CSN5,JAB 1,Jun activation domain binding protein 1,Jun activation domain binding protein,Jun activation domain-binding protein 1,MGC3149,MOV 34,MOV34,MOV34 family,38-KD member,SGN 5,SGN5,Signalosome subunit 5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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