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Anti-Human/Mouse COL8A2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02421
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human COL8A2
Specificity Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in cornea and sclera, and in the perichondrium of cartilaginous tissues. In the kidney, expressed in mesangial cells, glomerular endothelial cells, and tubular epithelial cells. Also expressed in mast cells, and in astrocytes during the repair process. Expressed in Descemet's membrane.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P25067
Concentration 0.4 mg/mL
Dilution IHC 1:25-100, ELISA 1:2000-5000
Formulation
Application IHC,ELISA
Other Names AI429819,Collagen,type VIII,alpha 2,FECD,FECD1,FLJ00201,MGC116970,MGC116972,MGC90765,PPCD,PPCD2,RP23-113P22.2,RP4-665N4.3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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