Anti-Human/Mouse COL11A1 Polyclonal Antibody

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02972
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human COL11A1
Specificity Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P12107
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names COBA1,COL11A1,COLL6,Collagen alpha 1,Collagen alpha-1(XI) chain,collagen XI alpha 1,collagen XI,alpha 1 polypeptide,collagen,type XI,alpha 1,STL2,STL3,XI chain precursor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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