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Anti-Human/Mouse CLEC4A Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12001
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CLEC4A
Specificity Expressed in dendritic cells, myeloid cells, B-cells and HL-60 cells (at protein level). TNF alpha, IL-1 alpha, and LPS, down-regulated expression at the surface of neutrophils (at protein level). Expressed preferentially in hematopoietic tissues. Expressed in peripheral blood leukocytes, neutrophils, moderate quantities in spleen, lymph node, and bone marrow, and at very low levels in thymus. Expressed in Ag-presenting cells (DC, monocytes, macrophages and B-cells), as well as on granulocytes. Expression was decreased in DC by signals inducing its maturation (e.g. CD40 ligand, LPS, and TNF alpha).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9UMR7
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names C type (calcium dependent carbohydrate recognition domain) lectin superfamily member 6,C type lectin,C type lectin DDB27,C type lectin superfamily 6,C-type (calcium dependent,carbohydrate-recognition domain) lectin, superfamily member 6,C-type lectin superfamily member 6,C-type lectin DDB27,C-type lectin domain family 4 member A,C-type lectin domain family 4,member A,C-type lectin domain family 4,member a2,C-type lectin superfamily member 6,CLC4A,Clec4a,Clec4a2,CLECSF6,DCIR,Dcir1,DDB27,Dendritic cell immunoreceptor,HDCGC13P,Lectin like immunoreceptor,Lectin,C-type,superfamily member 6,Lectin-like immunoreceptor,LLIR
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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