Anti-Human/Mouse Cleaved-CASP7 (S199) Polyclonal Antibody

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02108
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Caspase-7
Specificity Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P55210
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IHC-p,ELISA
Other Names Apoptotic protease Mch-3,Apoptotic protease MCH3,CASP-7,CASP7,CASP7,Caspase 7,Caspase 7 apoptosis related cysteine peptidase,Caspase-7 subunit p11,Caspase7,CMH 1,CMH-1,CMH1,ICE LAP3,ICE-LAP3,ICE-like apoptotic protease 3,LICE2,MCH3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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