Anti-Human/Mouse Cleaved-CASP7 p20 (D198) Polyclonal Antibody

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02123
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Caspase-7 p20
Specificity Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P55210
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:40000
Formulation
Application WB,ELISA
Other Names Apoptotic protease Mch-3,Apoptotic protease MCH3,CASP-7,CASP7,CASP7,Caspase 7,Caspase 7 apoptosis related cysteine peptidase,Caspase-7 subunit p11,Caspase7,CMH 1,CMH-1,CMH1,ICE LAP3,ICE-LAP3,ICE-like apoptotic protease 3,LICE2,MCH3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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