Anti-Human/Mouse CD316 Polyclonal Antibody

May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02593
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CD316.
Specificity Expressed in brain, kidney, testis, liver and placenta with moderate expression in all other tissues. Detected on a majority of B-cells, T-cells, and natural killer cells but not on monocytes, polynuclear cells and platelets.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q969P0
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names CD316,CD316 antigen,CD81 partner 3,CD81P3,EWI-2,EWI2,Glu-Trp-Ile EWI motif-containing protein 2,igsf-8,IgSF8,IGSF8,Immunoglobulin superfamily member 8,Immunoglobulin superfamily member 8 precursor,KCT-4,KCT4,Keratinocytes-associated transmembrane protein 4,LIR-D1,PGRL,Prostaglandin regulatory-like protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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