Anti-Human/Mouse CD130 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA02530
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from human CD130 around the non-phosphorylation site of Ser782.
Specificity	Found in all the tissues and cell lines examined. Expression not restricted to IL6 responsive cells.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	P40189
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application	WB,IHC-p,IF,ELISA
Other Names	CD130,CD130 antigen,CDw130,gp130,GP130 RAPS,IL 6R beta,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta,IL-6RB,IL6 ST,IL6RB,IL6ST,Interleukin 6 receptor subunit beta,Interleukin receptor beta chain,Interleukin-6 receptor subunit beta,Interleukin-6 signal transducer,Membrane glycoprotein 130,Membrane glycoprotein gp130,Oncostatin M receptor,Oncostatin M receptor alpha subunit,Oncostatin-M receptor subunit alpha
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse CD130 Polyclonal Antibody

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