Anti-Human/Mouse CARD11 Polyclonal Antibody

Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02437
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human CARD 11
Specificity Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLa S3, Molt-4, A549 and G431 cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9BXL7
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names 0610008L17Rik,2410011D02Rik,Bcl10 interacting maguk protein 3,BIMP 3,BIMP3,CAR11,CARD 11,CARD containing MAGUK protein 3,Card maguk protein 1,CARD-containing MAGUK protein 1,CARD11,CARD11 protein,Carma 1,CARMA1,Caspase recruitment domain containing protein 11,Caspase recruitment domain family member 11,Caspase recruitment domain-containing protein 11,MGC133069
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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