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Anti-Human/Mouse c-Kit Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07334
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human KIT
Specificity Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P10721
Concentration 0.4 mg/mL
Dilution IHC 1:25-100, ELISA 1:2000-5000
Formulation
Application IHC,ELISA
Other Names C Kit,c-Kit,c-Kit Ligand,CD117,Kit,Kit Ligand,KIT oncogene,KIT proto oncogene receptor tyrosine kinase,KIT,Mast cell growth factor receptor,Mast/stem cell growth factor receptor Kit,MGF,p145 c-kit,PBT,Piebald trait protein,Proto oncogene c Kit,Proto oncogene tyrosine protein kinase Kit,Proto-oncogene c-Kit,SCF Receptor,SCFR,soluble KIT variant 1,Steel Factor Receptor,Stem cell factor receptor,tyrosine protein kinase Kit,Tyrosine-protein kinase Kit,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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