Anti-Human/Mouse AURKC Polyclonal Antibody

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09885
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human AURKC
Specificity Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9UQB9
Concentration 0.1 mg/mL
Dilution WB 1:200-1:1000, IHC 1:15-1:50
Formulation
Application WB,IHC,ELISA
Other Names AURKC,AIE 2,Aie1,AIE2,AIK 3,AIK3,ARK 3,ARK-3,ARK3,Aur C,AurC,Aurkc,AURKC,aurora 3,Aurora C,Aurora kinase C,aurora related kinase 3,Aurora-related kinase 3,Aurora/Ipl1 related kinase 3,Aurora/Ipl1-related kinase 3,Aurora/Ipl1/Eg2 protein 2,EC 2.7.11.1,Serine threonine protein kinase 13,serine/threonine kinase 13 (aurora/IPL1 like),serine/threonine protein kinase aurora C,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase aurora-C,SPGF5,STK13
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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