Anti-Human/Mouse ASPN Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA09375
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human ASPN
Specificity	Higher levels in osteoarthritic articular cartilage, aorta, uterus. Moderate expression in small intestine, heart, liver, bladder, ovary, stomach, and in the adrenal, thyroid, and mammary glands. Low expression in trachea, bone marrow, and lung. Co-localizes with TGFB1 in chondrocytes within osteoarthritic (OA) lesions of articular cartilage.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q9BXN1
Concentration	0.6 mg/mL
Dilution	WB 1:500-1:2000
Formulation
Application	WB,ELISA
Other Names	ASPN,ASPN protein,ASPN,Asporin (LRR class 1),Asporin,Asporin proteoglycan,FLJ20129,LRR class 1,Periodontal ligament associated protein 1,Periodontal ligament-associated protein 1,PLAP 1,PLAP-1,PLAP1,SLRR 1C,SLRR1C,Small leucine rich protein 1C
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse ASPN Polyclonal Antibody

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