Anti-Human/Mouse APLF Polyclonal Antibody

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02056
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human APLF around the non-phosphorylation site of S116.
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8IW19
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
Formulation
Application WB,IHC-p,ELISA
Other Names 2010301N04Rik,AI452191,Aplf,APLF,Aprataxin and PNK-like factor,Apurinic-apyrimidinic endonuclease APLF,C2orf13,PNK and APTX like FHA protein,PNK and APTX-like FHA domain-containing protein,RGD1565557,XIP1,XRCC1 interacting protein 1,XRCC1-interacting protein 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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