Anti-Human/Mouse APIP Polyclonal Antibody

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11476
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human APIP
Specificity Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q96GX9
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Apaf1 Interacting Protein,APAF1-interacting protein,APIP,APIP2,CG129,CGI 29,CGI29,dJ179L10.2,MMRP19,Monocyte/macrophage protein 19,MTNB,MTRu 1 P dehydratase,MTRu-1-P dehydratase,Probable methylthioribulose 1 phosphate dehydratase,Probable methylthioribulose-1-phosphate dehydratase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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