Anti-Human/Mouse AP2A1 Polyclonal Antibody

This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02412
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human AP2A1
Specificity Isoform A expressed in forebrain, skeletal muscle, spinal cord, cerebellum, salivary gland, heart and colon. Isoform B is widely expressed in tissues and also in breast cancer and in prostate carcinoma cells.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O95782
Concentration 0.3 mg/mL
Dilution WB 1:200-1000, IHC 1:20-100, ELISA 1:1000-2000
Formulation
Application WB,IHC,ELISA
Other Names 100 kDa coated vesicle protein A,Adapter-related protein complex 2 alpha-1 subunit,adapter-related protein complex 2 subunit alpha-1,Adaptin alpha A,Adaptin alpha,Adaptor protein complex AP 2 alpha 1 subunit,adaptor protein complex AP 2 subunit alpha 1,Adaptor protein complex AP-2 subunit alpha-1,Adaptor protein complex AP2 alpha 1 subunit,adaptor protein complex AP2 subunit alpha 1,Adaptor related protein complex 2 alpha 1 subunit,Adaptor related protein complex AP 2 alpha 1 subunit,Adaptor related protein complex AP2 alpha 1 subunit,ADTAA,Alpha A adaptin,Alpha adaptin A,Alpha-adaptin A,alpha1 adaptin,Alpha1-adaptin,AP 2 alpha,AP 2 complex subunit alpha 1,AP-2 complex subunit alpha-1,AP2 complex subunit alpha 1,AP2-ALPHA,Ap2a1,AP2A1,CLAPA 1,CLAPA1,Clathrin adaptor complex AP2. alpha subunit,Clathrin assembly protein complex 2 alpha A large chain,Clathrin assembly protein complex 2 alpha-A large chain,Clathrin associated / assembly / adaptor protein large alpha 1,clathrin associated assembly adaptor protein large alpha 1,clathrin associated/assembly/adaptor protein,large,alpha 1,Plasma membrane adaptor HA 2/AP 2 adaptin alpha A subunit,Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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