Anti-Human/Mouse ADNP Polyclonal Antibody

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03052
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human ADNP
Specificity Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9H2P0
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names Activity dependent neuroprotective protein,Activity dependent neuroprotector,Activity-dependent neuroprotective protein,Activity-dependent neuroprotector homeobox protein,Adnp,ADNP,KIAA0784
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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